Hyperhidrosis is characterized by excessive sweating that occurs in the hands (palmar hyperhidrosis), in the armpits (axillary hyperhidrosis), or in the feet (plantar hyperhidrosis). The initial treatment for hyperhidrosis usually involves topical or oral medications. Another option is iontophoresis. A newer treatment for hyperhidrosis is Botox. A small amount of Botox is injected to help stop those areas from getting clammy and sweaty. Botox injections are only temporary and usually are repeated two times a year.